Role of Interleukin-6 in Type 1 Diabetes Mellitus (Review of Articles)
نویسندگان
چکیده
Type one diabetes mellitus (T1DM) is an autoimmune condition wherein islet cells of pancreas are damaged, necessitating extrinsic insulin therapy for the remainder life. T1DM affects kids and teenagers accounts roughly 5-10% cases. Cytokines low-molecular-weight extracellular molecules that serve as immune modulators which cause β impairment in patients by generating nitric-oxide. Comprehending controlling inflammatory factors, on contrary, may aid treating or even avoiding disease advancement. Interleukin-6 (IL-6) a versatile mediator have influential purpose inflammation besides conditions variables implicated inflammation. This cytokine, however, was demonstrated to play significant function metabolic control, notably homeostasis glucose.Objective this review demonstrate contribution interleukine-6 etiology.
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ژورنال
عنوان ژورنال: Annals of the College of Medecine
سال: 2023
ISSN: ['2309-6217', '0027-1446']
DOI: https://doi.org/10.33899/mmed.2023.137090.1175